Mag2 Stickpack Oral Solution 1.5 g/10 ml Magnesium Pidolate 20 Sachets

Magnesium deficiency states.

Hypersensitivity to the active substance or to any of the excipients. Severe renal insufficiency (creatinine clearance less than 30 mL / min). Not to be administered in subjects undergoing digitalis therapy.

For adults only : 3 vials or 3 single-dose sachets of solution or 2 sachets of powder per day. In children, the dosage can be established by the doctor previously consulted. Warning: use only for short periods of treatment.

In patients with renal insufficiency it is necessary to reduce the dosage and to monitor renal function and magnesaemia. Consideration should be given to the possibility of cardiovascular and respiratory depression occurring during treatment. Each vial of MAG2 solution contains 3.5 g of sucrose. Each single-dose sachet of MAG2 solution contains 3.5 g of sucrose. Each sachet of MAG2 powder contains 2.985 g of sucrose. If taken in accordance with the recommended dose, the daily intake of sucrose corresponds to 10.5 g for the vials and single-dose sachets of solution and 5.97 for the powder sachets. Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption, or sucrase-isomaltase deficiency should not take this medicine. MAG2 oral solution contains p-hydroxybenzoates: they can cause allergic reactions (even delayed) and, exceptionally, bronchospasm.

Administration of magnesium by mouth can result in reduced absorption of tetracyclines, therefore it is recommended not to administer MAG2 at the same time as tetracycline-based drugs, but to maintain at least 3–4 hours of distance between the two administrations. Quinolones should be administered at least 2 hours before or 6 hours after administration of magnesium-based products to avoid interference with their absorption. In the case of concomitant administration of products based on magnesium and cholecalciferol (vitamin D3), it is recommended to control the calcium level to avoid the possible occurrence of hypercalcemia. The concomitant use of preparations containing calcium or phosphate salts is not recommended as these products prevent the absorption of magnesium. Simultaneous intake of magnesium-based products with CNS depressants can potentiate the CNS effects of magnesium and should be carefully evaluated.

Rare digestive disorders, diarrhea, abdominal pain. Exceptional cases of individual intolerance to magnesium have been reported, which can be treated with oral or parenteral antihistamines.

During pregnancy and breastfeeding, it is advisable to take the drug under medical supervision and in cases of real need. Magnesium is considered compatible with breastfeeding.