Xamamine 50mg Dimenhydrate Antiemetic 6 Softgels

Therapeutic indications
Xamamina Chewable Gums is a medicine used to treat phenomena such as seasickness, plane, car and train sickness.

Dosage and method of use
In adults 1 medicated chewing gum at the first symptoms of nausea; the effect lasts about 4 hours. If necessary, repeat the dose after 3-4 hours, up to a maximum of 4 medicated chewing gums in 24 hours. In children between 4 and 12 years of age 1 medicated chewing gum half an hour before travel or at the first symptoms of nausea and vomiting and if necessary repeat the dose after 6-8 hours, up to a maximum of 2 gum chew medicated within 24 hours.

Contraindications

Special warnings
Xamamina should be administered with caution in subjects suffering from narrow-angle glaucoma, prostatic hypertrophy, urinary retention, slowed intestinal transit, bronchial asthma, epilepsy, porphyria. The product may mask the symptoms of ototoxicity and therefore should be administered with caution to patients receiving ototoxic drugs.
Soft capsules and medicated chewing gum contain sorbitol: patients with rare hereditary problems of fructose intolerance should not take this medicine. The soft capsules contain parabens which can cause allergic reactions (including delayed ones).

Pregnancy and breastfeeding

In reproductive studies in rats and rabbits, doses 20-25 times higher than those normally used in therapy in humans did not show teratogenic effects or impaired fertility. However, no data are available on the use of the product in pregnant women. Therefore, although the teratogenicity of the product appears unlikely, the use of dimenhydrinate in pregnancy is contraindicated.

Small amounts of dimenhydrinate pass into breast milk. Given the possible adverse events of the product in infants, the use of dimenhydrinate during lactation is
contraindicated.

Expiry and retention
Xamamina must be stored at temperatures not exceeding 25 °.

Warning: do not use the medicine after the expiry date indicated on the package.

Composition
Xamamina contains, for each capsule:
Active ingredient: dimenhydrinate 25 mg;
Core: Type A methacrylic acid copolymer, sorbitol, mint flavor, magnesium stearate, gum base, levomenthol, aspartame, talc, colloidal silica, anhydrous tricalcium phosphate;
Coating: hypromellose, macrogol 6000, titanium dioxide, quinoline yellow (E104), patent blue V (E131).