Glycerol Sofar Adults 2250mg Laxative 18 Suppositories

Suppositories for rectal use based on glycerol.

Therapeutic indications

Glycerol Sofar Adults in suppositories is indicated for the short-term treatment of occasional constipation.

Dosage and posology

The correct dose is the minimum sufficient to produce an easy evacuation. It is advisable to initially use the minimum doses provided.

• Adults and adolescents (12 - 18 years): 1 adult suppository as needed, for a maximum of 1 or 2 doses per day.

Laxatives should be used as infrequently as possible for no more than seven days. A diet rich in liquids favors the effect of the medicine.

Method of administration

Remove the suppository from its container and then, if necessary, moisten it to facilitate its rectal introduction. If the suppositories appear soft, immerse the containers, before opening them, in cold water.

Overdose

No cases of overdose have been reported. In any case, excessive doses (laxative abuse - frequent or prolonged use or with excessive doses) can cause abdominal pain, persistent diarrhea with consequent loss of water, mineral salts (especially potassium) and other essential nutritional factors. Leaking fluids and electrolytes must be replaced. Electrolyte imbalances are characterized by the following symptoms: thirst, vomiting, weakness, edema, bone pain (osteomalacia) and hypoalbuminemia. In the most serious cases, the onset of dehydration or hypokalaemia is possible, which can cause cardiac or neuromuscular dysfunctions, especially in the case of simultaneous treatment with cardiac glycosides, diuretics or corticosteroids. The abuse of laxatives, especially contact laxatives (stimulant laxatives), can cause addiction (and, therefore, the possible need to gradually increase the dosage), chronic constipation and loss of normal intestinal functions (intestinal atony). In case of accidental ingestion / intake of an excessive dose of glycerol, notify your doctor immediately or go to the nearest hospital.

Contraindications

Glycerol Sofar Adult suppositories are contraindicated in case of:

• Hypersensitivity to the active substance or to any of the excipients
• acute abdominal pain or of unknown origin
• nausea or vomiting
• intestinal obstruction or stricture
• rectal bleeding of unknown origin
• acute hemorrhoidal crisis with pain and bleeding
• severe state of dehydration

Side effects

Like all medicines, glycerol can cause side effects, although not everybody gets them. Below are the side effects of glycerol. Insufficient data are available to establish the frequency of the individual effects listed.

• Gastrointestinal disorders: Isolated cramping pains or abdominal colic and diarrhea, with loss of fluids and electrolytes, more frequent in cases of severe constipation, as well as rectal irritation.

Pregnancy and breastfeeding

Ask your doctor or pharmacist for advice before taking any medicine. There have been no adequate and well-controlled studies on the use of the medicine in pregnancy or lactation. Although there are no obvious contraindications to the use of the medicine during pregnancy and breastfeeding, it is recommended to take the medicine only in case of need and under medical supervision.

Special warnings

Laxatives should be used as infrequently as possible and for no more than seven days. Use for longer periods of time requires a doctor's prescription after adequate evaluation of the individual case. The treatment of chronic or recurrent constipation always requires the intervention of the doctor for the diagnosis, the prescription of drugs and the surveillance during the course of therapy. The abuse of laxatives can cause persistent diarrhea with consequent loss of water, mineral salts (especially potassium) and other essential nutritional factors. In the most severe cases of abuse it is possible the onset of dehydration or hypokalaemia, which can lead to cardiac or neuromuscular dysfunctions, especially in the case of simultaneous treatment of cardiac glycosides, diuretics or corticosteroids.

The abuse of laxatives, especially contact laxatives (stimulant laxatives), can cause addiction (and, therefore, the possible need to gradually increase the dosage), chronic constipation and loss of normal intestinal functions (intestinal atony). In episodes of constipation it is first of all recommended to correct eating habits by integrating the daily diet with an adequate intake of fiber and water. When using laxatives it is advisable to drink at least 6-8 glasses of water or other liquids a day, in order to facilitate the softening of the stool.

Tell your doctor or pharmacist if you have recently taken any other medicines, even those without a prescription. No specific interaction studies have been performed.

Consult your doctor when the need for the laxative derives from a sudden change in previous bowel habits (frequency and characteristics of bowel movements) lasting more than two weeks or when the use of the laxative fails to produce effects. In children under the age of twelve, the medicine can only be used after consulting your doctor. It is also advisable that elderly people or those in poor health conditions consult their doctor before using the medicine.

Expiry and retention

Check the expiration date indicated on the package. Store in the original package in order to protect from moisture and away from direct heat sources. The expiry date refers to the product in intact packaging, correctly stored.

Warning : do not use the medicine after the expiry date indicated on the package.

Composition

One suppository of Glycerol Sofar Adults 2250 mg contains:

Active principle

Glycerol 2250 mg.

Excipients

Sodium stearate, sodium bicarbonate.