Macrolax 1 Bottle 120ml Rectal Solution

NAME
MACROLAX 36 G + 0.24 G RECTAL SOLUTION

PHARMACOTHERAPEUTIC CATEGORY
Gastrointestinal systems and metabolisms; constipation medications; enemas; sodium docusate, including combinations.

ACTIVE PRINCIPLES
Non crystallizable liquid sorbitol; sodium docusate.

EXCIPIENTS
Methyl parahydroxybenzoate, purified water.

INDICATIONS
Short-term treatment of occasional constipation.

CONTRAINDICATIONS / SECONDARY EFFECT
Hypersensitivity 'to the active ingredients or to any of the listed excipients; laxatives are contraindicated in subjects with acute abdominal pain or of unknown origin, nausea or vomiting, intestinal obstruction, rectal bleeding of unknown origin, severe dehydration; generally contraindicated during pregnancy and lactation; generally contraindicated in pediatric age.

DOSAGE
All contents of the bottle for an enema. The correct dose is the minimum sufficient to produce an easy evacuation of soft faeces. It is advisable to initially use the minimum doses provided. Do not exceed the recommended dose. Take preferably in the evening. Laxatives should be used as infrequently as possible and for no more than seven days. Use for longer periods of time requires a doctor's prescription after adequate evaluation of the individual case. A diet rich in liquids favors the effect of the medicine.

STORAGE
This medicine does not require any special storage conditions.

WARNINGS
The abuse of laxatives (frequent or prolonged use or with excessive doses) can cause persistent diarrhea with consequent loss of water, mineral salts (especially potassium) and other essential nutritional factors. In the most severe cases the onset of dehydration or hypokalaemia is possible which can cause cardiac or neuromuscular dysfunctions, especially in the case of simultaneous treatment with cardiac glycosides, diuretics or corticosteroids. The abuse of laxatives, especially contact laxatives (stimulant laxatives), can cause addiction (and, therefore, possible need to gradually increase the dosage), chronic constipation and loss of normal intestinal functions (intestinal atony). The treatment of chronic or recurrent constipation always requires the intervention of the doctor for the diagnosis, the prescription of drugs and the surveillance during the course of therapy. Consult your doctor when the need for the laxative derives from a sudden change in previous bowel habits (frequency and characteristics of bowel movements) lasting more than two weeks or when the use of the laxative fails to produce effects. It is also advisable that elderly people or those in poor health conditions consult their doctor before using the medicine. Pediatric population: in children under 12 years the medicine can 'be used only after consulting your doctor. Contains methyl parahydroxybenzoate.

INTERACTIONS
This product should not be used in conjunction with other medications and mineral oil or laxatives that contain it. Laxatives can reduce the time spent in the intestine, and therefore the absorption, of other drugs administered simultaneously orally. Therefore, avoid taking laxatives and other drugs at the same time: after taking a medicine, leave an interval of at least 2 hours before taking the laxative.

SIDE EFFECTS
Occasionally: isolated cramping pains or abdominal colic, more frequent in cases of severe constipation. The reporting of suspected adverse reactions that occur after the authorization of the drug is important, as it allows continuous monitoring of the benefit / risk ratio of the drug.

PREGNANCY AND BREASTFEEDING
There are no adequate and well-controlled studies on the use of the medicinal product in pregnancy or breastfeeding. Therefore, the medicine should be used only in case of need ', after evaluating the expected benefit to the mother in relation to the possible risk to the fetus or infant.