Normase 66.7% Lactulose Laxative Syrup Bottle 200ml

NAME
NORMASE 66.7% SYRUP 200 ML BOTTLE

PHARMACOTHERAPEUTIC CATEGORY
Constipation medications.

ACTIVE PRINCIPLES
100 ml of syrup contain: lactulose 66.7 g. 15 ml of syrup contains 10 g of lactulose.

EXCIPIENTS
Citric acid, Curt Georgi aroma n. 7 bis, purified water.

INDICATIONS
Short-term treatment of occasional constipation.

CONTRAINDICATIONS / SECONDARY EFFECT
Hypersensitivity 'to the active substance or to any of the excipients. Galactosemia. Laxatives are contraindicated in subjects with acute abdominal pain or of unknown origin, nausea or vomiting, intestinal obstruction or stenosis, rectal bleeding of unknown origin, severe dehydration. Generally contraindicated during pregnancy and breastfeeding. Generally contraindicated in pediatric age.

DOSAGE
The correct dose is the minimum sufficient to produce an easy evacuation of soft faeces. It is advisable to initially use the minimum doses provided. When necessary, the dose can then be increased, but without ever exceeding the maximum indicated. Adults: the starting dose is usually 20 ml per day followed by 10 ml per day as a maintenance dose. In some subjects a higher starting dose (30-40 ml) may be required which must then be progressively reduced to the normal maintenance dose. In sensitive subjects it is advisable instead to start with lower doses. Children: 5 to 15ml per day, depending on body weight. Infants: half - 1 ml per day for each kg of body weight. The quantities indicated above can also be taken in a single daily dose, preferably in the morning on an empty stomach or in the evening before a meal. Laxatives should be used as infrequently as possible and for no more than seven days. The use for longer periods of time requires the prescription of the doctor after adequate evaluation of the individual case. Ingest together with an adequate quantity of water (a large glass). A diet rich in liquids favors the effect of the medicine.

STORAGE
No special storage precautions.

WARNINGS
The abuse of laxatives (frequent or prolonged use or with excessive doses) can cause persistent diarrhea with consequent loss of water, mineral salts (especially potassium) and other essential nutritional factors. In the most severe cases the onset of dehydration or hypokalaemia is possible which can cause cardiac or neuromuscular dysfunctions, especially in the case of simultaneous treatment with cardiac glycosides, diuretics or corticosteroids. The abuse of laxatives, especially contact laxatives (stimulant laxatives), can cause addiction (and, therefore, possible need to gradually increase the dosage), chronic constipation and loss of normal intestinal functions (intestinal atony). The active ingredient is a poorly absorbable and non-metabolized sugar. Due to the presence of other sugars, such as lactose, galactose and tagatose, it is necessary for diabetic patients to inform the doctor. Patients on digital therapy should consult their physician before starting therapy. In children under 12 years of age, the medicine can only be used after consulting your doctor. The treatment of chronic or recurrent constipation always requires the intervention of the doctor for the diagnosis, the prescription of drugs and the surveillance during the course of therapy. Consult your doctor when the need for the laxative derives from a sudden change in previous bowel habits (frequency and characteristics of bowel movements) that has lasted for more than two weeks or when the use of the laxative fails to produce effects. It is also advisable for elderly people or those in poor health to consult their doctor before using the medicine.

INTERACTIONS
Broad-spectrum bactericidal agents and antacids, administered simultaneously with lactulose, can reduce its degradation by limiting the acidifying effect of the intestinal contents and, consequently, the therapeutic efficacy. On the other hand, a synergistic effect with neomycin is possible. Laxatives can reduce the time spent in the intestine, and therefore the absorption, of other drugs administered simultaneously orally. Therefore, avoid ingesting laxatives and other drugs at the same time: after taking a medicine, leave an interval of at least two hours before taking the laxative.

SIDE EFFECTS
Occasionally: isolated cramping pains or abdominal colic, more frequent in cases of severe constipation, flatulence. These symptoms are usually mild and subside spontaneously after the first days of treatment. Only in case of onset of diarrhea it is advisable to reduce the dosage or possibly suspend the treatment. After prolonged treatment, loss of electrolytes may occur.

PREGNANCY AND BREASTFEEDING
There are no adequate and well-controlled studies on the use of the medicinal product in pregnancy or breastfeeding. Therefore the medicine should be used only in case of need, under the direct supervision of the doctor, after evaluating the expected benefit for the mother in relation to the possible risk for the fetus or infant.