Pevaryl 150 mg econazole nitrate 6 vaginal ovules

Description

PEVARYL 1% vaginal cream 100 g of vaginal cream contain: active ingredient: econazole nitrate 1g. Excipients with known effects: butylhydroxyanisole; benzoic acid. PEVARYL 50 mg eggs 1 egg contains: active ingredient: econazole nitrate 50 mg. PEVARYL 150 mg eggs 1 egg contains: active ingredient: econazole nitrate 150 mg. PEVARYL 150 mg prolonged-release egg 1 prolonged-release egg contains: active ingredient: micronized econazole nitrate 150 mg. PEVARYL 1% cutaneous solution for external genitalia 100 ml of cutaneous solution for external genitalia contain: active ingredient: econazole 1.033 g

Therapeutic indications

Vulvovaginal mycoses Fungal balanitis

Method of conservation
Prolonged-release pessaries and pessaries: do not store above 30 ° C. Vaginal cream: do not store above 25 ° C.

Warnings
Pevaryl Vaginal Cream and Pessaries are for intravaginal use only. Pevaryl is not for ophthalmic or oral use. The simultaneous use of latex condoms or diaphragms with vaginal antimicrobial preparations may decrease the effectiveness of the latex contraceptive. Therefore, products such as PEVARYL should not be used in conjunction with latex diaphragms or condoms. Patients using spermicides should consult their doctor as any local vaginal treatment can render the spermicide inactive. PEVARYL must not be used together with other products for internal or external treatment of the genitals. Should marked irritation or sensitization occur, the treatment should be discontinued. Patients sensitive to imidazoles may be sensitive to econazole nitrate. Important information about some of the ingredients PEVARYL contains butylated hydroxyanisole. It can cause local skin reactions (e.g. contact dermatitis) or irritation of the eyes and mucous membranes. PEVARYL contains benzoic acid. Slightly irritating to the skin, eyes and mucous membranes.

Overdose

Adverse events associated with overdose or misuse of PEVARYL should be consistent with the adverse drug reactions listed in section 4.8 (Undesirable effects). Pevaryl is for topical use only. In case of accidental ingestion, treat with symptomatic therapy. If the product is accidentally applied to the eyes, wash with clean or saline water and consult a doctor if symptoms persist.

Pregnancy and breastfeeding

Pregnancy Animal studies have shown reproductive toxicity. Due to vaginal absorption, PEVARYL should not be used in the first trimester of pregnancy unless the doctor considers it necessary for the patient's health. PEVARYL can be used during the second and third trimesters if the potential benefits outweigh the possible risks to the fetus. Lactation After oral administration of econazole nitrate to lactating rats, econazole and its metabolites were excreted in milk and found in pups. It is not known whether econazole nitrate is excreted in human milk. Use PEVARYL with caution in breastfeeding patients. Fertility Results from animal reproduction studies showed no effects on fertility